Endocrine Abstracts

Background: Thyroid ultrasound (US) is not routinely used in the evaluation of hyperthyroidism, although studies show that clinical exam may miss lesions up to 2 cm in diameter. We reviewed our department’s practice of thyroid US to consider (1) accuracy of our clinical diagnosis and (2) whether this could improve management. Our hospital has no facility for isotope scanning.Methods: Seventy-three cases (13 male, 60 female) identified from thyroid U...

Introduction: Hypothyroidism remains a global problem with prevalence of 1–2% in iodine replete areas of the world. Primary or Autoimmune Hypothyroidism remains the most common type of hypothyroidism worldwide. Central (secondary) hypothyroidism (CH) because of pituitary/hypothalamic disorders is a rare cause of hypothyroidism with reported prevalence of 1:20.000 to 1:80.000 in the general population1. This makes CH about 1000 fold rarer than primary hypothyro...

Background and aims: Thiazolidinediones have been extensively used as second line agents in the management of type 2 diabetes. A small increased incidence of ischaemic heart disease was suggested by a meta-analysis of studies using Rosiglitazone. Similar meta-analysis of Pioglitazone did not show adverse cardiovascular outcomes. Our aim was to objectively evaluate the changes in glycaemic and lipid control in a controlled conversion from Rosiglitazone to Pioglitazone.<p cl...